Backed by Solid Research
Key Potential Benefits
Digestive Health:
- Lowers the chance of diarrhea from antibiotics (22.4% to 12.3%).
- Helps prevent and treat different types of diarrhea.
Key Potential Benefits
Immune Support:
- Boosts the production of antibodies.
- Helps your body fight infections better.
Key Potential Benefits
Anti-Inflammatory Effects:
- Reduces inflammation in the body.
- Helps with conditions like gut problems (IBD)
Why LGG Is Different
Lactobacillus rhamnosus GG is the most clinically studied probiotic strain in the world. Not all probiotics are created equal. Here is why LGG stands alone.
Most Studied Strain on Earth
More human clinical trials than any other probiotic strain. Decades of safety and efficacy data across all age groups.
30 Billion CFU Per Serving
Clinical-strength dosing in every single serving. Most competitors use 1-10 billion CFU. We use 30 billion because that is what the research supports.
90 Capsules, Full Supply
A full 3-month supply in one bottle. Subscribe and save 15% so your next bottle ships automatically before you run out. Never miss a day.
Proven Gut Protection
Clinical trials show LGG cuts antibiotic-associated diarrhea nearly in half. From 22.4% incidence down to 12.3%.
Third-Party Tested
Every batch tested by Eurofins. Made in a cGMP and NSF-certified facility. No fillers, no proprietary blends, no guesswork.
6-Month Money Back
If you do not feel a difference, you get every cent back. No questions. No hassle. We bet on the product because the science already did.
How We Stack Up
Third-party tested, clinically dosed, and priced to win.
| Wise Choice | Culturelle | Garden of Life | |
|---|---|---|---|
| Strain | LGG Only | LGG + fillers | Multi-strain |
| CFU / Serving | 30 Billion | 10 Billion | 15 Billion |
| Capsules | 90 | 30 | 30 |
| Testing | Eurofins | Undisclosed | Undisclosed |
| Guarantee | 180 Days | 30 Days | 30 Days |
| Per Serving | ~$0.27 | ~$0.87 | ~$1.07 |
Save More, Gut Better
Consistency builds a healthy microbiome. The longer you commit, the better the results.
Frequently Asked Questions
What is Lactobacillus rhamnosus GG (LGG)? +
How many CFU are in each serving? +
How should I take this supplement? +
What makes this different from other probiotics? +
Is there a money-back guarantee? +
Are there any side effects? +
Do you offer subscriptions? +
Questions & Answers
Real questions from our customers.
What makes LGG different from multi-strain probiotic blends?
Most multi-strain probiotics use 10-15 strains at low doses that can compete with each other. LGG is a single clinically studied strain at 30 billion CFU, backed by over 1,800 published studies showing targeted results for IBS, antibiotic-associated diarrhea, and immune support.
Is 30 billion CFU too much for a probiotic?
No. Clinical studies on LGG used doses between 10-40 billion CFU for therapeutic results. 30 billion is in the clinical sweet spot with decades of safety data and no reported adverse effects at this dosage.
How does Wise Choice LGG compare to Culturelle?
Culturelle uses LGG at 10 billion CFU with 30 capsules per bottle. Wise Choice uses 30 billion CFU with 90 capsules. Cost per serving is approximately $0.27 versus $0.87 for Culturelle. Same strain, 3x the potency, 3x the supply, third-party tested by Eurofins, with a 180-day money-back guarantee.
Does this probiotic need to be refrigerated?
No refrigeration required. Capsules are shelf-stable and manufactured in a cGMP and NSF-certified facility to maintain potency at room temperature.
Can I take LGG probiotics while on antibiotics?
Yes. Clinical research shows LGG taken alongside antibiotics reduced diarrhea incidence from 22.4% to 12.3%. Take it at least 2 hours apart from your antibiotic dose and continue for 1-2 weeks after finishing the course.
Is LGG probiotic safe for children?
LGG is one of the most extensively studied probiotics in pediatric research, shown to support immune function and reduce duration of common infections in children. Consult your pediatrician before starting any new supplement for children.
Does LGG help with bloating?
Yes. LGG reduces bloating, gas, and abdominal discomfort by restoring microbial balance and strengthening the intestinal barrier. Most users report improvement within 2-4 weeks of consistent use.
What is the difference between LGG and Lactobacillus acidophilus?
Acidophilus primarily lives in the small intestine and helps with lactose digestion. LGG colonizes the large intestine with over 1,800 clinical studies demonstrating benefits for immune function, diarrhea prevention, IBS relief, and skin conditions. LGG adheres to the intestinal wall longer than most strains.
How long does it take for LGG probiotics to work?
Most people notice digestive improvements within 1-2 weeks. Immune benefits build over 4-8 weeks of consistent daily use at 30 billion CFU.
Can I take LGG with other supplements like multivitamins and fish oil?
Yes. LGG has no known interactions with vitamins, minerals, fish oil, or other common supplements. Only space it 2 hours apart from antibiotics.
Can LGG probiotics help with eczema and skin conditions?
Clinical trials show LGG can reduce atopic dermatitis severity through gut-skin axis modulation. A Lancet study found LGG supplementation reduced eczema incidence by nearly 50% in at-risk children. Evidence is promising for adults with inflammatory skin conditions as well.
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